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Song Beomjong

Base Editors

Methods and Protocols

AutorSong Beomjong
QuelleSonstige Datenquellen
ISBN978-1-0716-2881-2
Lieferbarkeitlieferbar
KatalogisatBasiskatalogisat
VerlagSpringer US
Erscheinungsdatum04.01.2024
Buch | Kartoniert
139,09 €
inkl. 7% MwSt.

Beschreibung (Langtext)

This volume explores base editors (BEs), an invaluable CRISPR-based genome editing tool with a wide variety of versatile applications. Beginning with an overview of BEs, their diverse variants, and computational tools, the book continues with experimental applications of BEs for disease modeling in mammalian cells and generating mutagenic mice, therapeutic base editing strategies, which covers delivery methods of BE-encoded DNA plasmids, mRNAs, or ribonucleoproteins through viruses or non-viral lipid nanoparticles, and lastly, the use of BEs in plants and bacteria. Written for the highly successful
Methods in Molecular Biology
series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 


Authoritative and practical,
Base Editors: Methods and Protocols
serves as an ideal guide for researchers looking to use base editors to continue their studies in an array of fields.

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