Genetic variants of the scavenger receptor class B type I
| Autor | |
| Quelle | Sonstige Datenquellen |
| ISBN | 978-3-639-78999-7 |
| Lieferbarkeit | lieferbar |
| Katalogisat | Basiskatalogisat |
| Verlag | AV Akademikerverlag |
| Erscheinungsdatum | 01.01.2015 |
Beschreibung (Langtext)
Scavenger receptor class B type I (SR-BI) plays a central role in high-density lipoprotein (HDL) metabolism. Its major role in cholesterol uptake and reverse cholesterol transport (RCT) has been confirmed in several mouse studies. The role of SR-BI in humans is unclear. A newly described missense mutation of SR-BI (P297S) was found in patients with elevated levels of HDL cholesterol. We aimed to investigate the influence of this mutation on the interaction between SR-BI and HDL.
